About Us

Peptone is a category-defining translational biophysics company focusing on the intersection of physics, biology and supercomputing. Currently, we are in the scale up phase, where our efforts go into building out our experimental lab capacity in Switzerland while growing the HPC and ML teams in the UK.

Our interdisciplinary team consists of physicists, biologists, computational chemists, software engineers and mathematicians. We have created a company culture that is based on scientific and personal integrity and a highly supportive, inclusive attitude. Our curiosity and drive stem from the shared passion to contribute to our scientific understanding of proteins and to translate these insights into reality by developing drugs that make people’s lives better.

Corporate Culture

Default to transparency. As individuals, we view transparency as a lifestyle of authenticity, respect, and honesty. As a team, we view transparency as an effective way to work remotely and establish a culture of trust.

Cultivate positivity. We strive to approach things in a positive way while realizing all emotions are valid. We encourage constructive feedback from team members and business partners to foster positive collaborations.

Show gratitude. We regularly stop and demonstrate gratitude for our circumstances. We are reverent to our team, investors, advisors, and commercial partners who believed in us from the beginning and will always use this as a guiding light to growth.

Practice reflection. We believe the act of introspection is where true learning and life-changing adjustments originate. We approach discussions intentionally and think through all angles.

Improve consistently. We are biased toward action and have a higher expectation of ourselves and of our technology than others have of us. We aim to be fully engaged in our work and activities, and fully disconnected when we’re not working.

Act beyond yourself. We consider the bigger picture, knowing our work goes beyond ourselves. We are not afraid of the less-traveled path if it holds true to our values and betters the world.

Build Sustainably. Sustainability is at the core of our technology, research, and team values. Oppenheimer’s supercomputer runs on 100% renewable energy and mitigates the need for traditional high-throughput experiments in our Swiss lab. Our team is incentivized and committed to growing a sustainable future and corporate culture.

Diversify. Diversity at all levels is paramount in translating biophysics to first in-class medicines while embracing the serendipity of science. Diversity in mindsets, gender, skills, backgrounds, and — because we are geeks, protein sequences — are key to building an impactful future for our patients.

Patient Passion. Our team is interwoven with a passion for understanding the “why” of protein drug failures to avoid them. The integration of the Oppenheimer platform with our Swiss pre-clinical laboratory is an unwavering commitment to developing first-in-class protein therapeutics for our patients.

Reverence to the giants. We embrace the fortitude and ingenuity of all the great minds and teams who advanced the field of protein biophysics to enable cutting-edge therapeutics. It is our honor to collaborate in this arena to pay homage to scientists who laid the very foundation.

Committed to our Corporate Culture to embrace diversity, Peptone Ltd and affiliates are Equal Opportunity and Affirmative Action employers building a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Our Mission

Delivering first-in-class medicines for better patient outcomes is our obsession. Translating biophysics of intrinsic protein disorder to generate de novo protein therapeutics is our passion.

What we bring…

  • A non-hierarchical environment where everyone has a voice to influence and shape the company’s future direction
  • An appreciative atmosphere with fair salaries, company benefits and top class working equipment
  • A highly dynamic environment with plenty of opportunities for career development
  • A highly skilled and interdisciplinary team that is passionate about proteins, science and business
  • A unique company giving you the opportunity to push the boundaries of biopharmaceutical drug development
  • A fast-paced company with novel science and academic rigor at its core
  • A company that values your contribution to scientific endeavor and supports presentation and publication of your novel discoveries
  • A flexible working setup to ensure a work-life balance

About the role

You work in a highly collaborative, team-oriented and fast-paced startup environment with a strong commitment to deliver and in ways that cut across traditional industry boundaries. You are integrated in an interdisciplinary team with matrix organizational structure, in which your main responsibility will be to plan, organize and execute discovery campaigns of therapeutic binders. You closely interact with project managers, assay engineers and biophysics leads to efficiently realize binder selection, characterization and optimization. As a strong expert in your field, you evaluate and establish novel selection strategies and help to integrate them in our Oppenheimer platform and pipeline. You are exposed to a wide range of cross functional tasks through which you can shape the future direction of the company, offering excellent opportunities for your personal development.

What you’ll do

  • Own and drive discovery research projects with an active role in therapeutic binder selection and all other related activities towards Candidate Selection and IND.
  • Be the main point of contact and Program Lead for Peptone’s first research project.
  • Support CSO and C-Suite on R&D strategy for early drug discovery and present at internal and external meetings such as Board meetings.
  • Act as lead for cross functional team internally and externally, guiding experimental design within the context of target biology.
  • Manage and organize the collaboration with CRO’s e.g. For selection, screening and functional profiling campaigns and other service providers.
  • Liaise with scientists in-house and at CROs to apply multiple cutting-edge selection techniques, driving the programme to candidate selection and beyond including scoping of TPP. Draft SoW and workplans for CRO engagements.
  • Where necessary, work closely with external consultants to gain valuable insight on program specific questions.
  • Guide experimental design and troubleshooting. Generate hypotheses to test, troubleshoot issues, design and execute the next set of experiments with the input from Peptone team.
  • Document the results in a detailed manner and in internal databases. Generate word document updates as well as slide summaries. Ensure cross-functional team fertilization of ideas.
  • Provide regular internal and external updates on program progress, risks, mitigation plans and budget updates working closely with the project manager.
  • Present research updates and participate constructively in working project teams and at laboratory group meetings.
  • Analyze and evaluate experimental data and summarize findings and relevance to both project and company objectives.
  • Be accountable for consistency, reliability and credibility of data internally and externally generated.
  • Comply to industry standards of good research practice principles, including relevant documentation procedures, eLNs etc

What you Bring

  • Ph.D. in Chemical/Biochemical Engineering, Biochemistry, Immunology, Molecular Biology or a related field.
  • 5 years of relevant research experience is required.
  • Proven experience in program leadership within large or small biotech/pharma companies
  • Proven experience in driving early biologics drug discovery research.
  • Experience in a subset of the following areas is desirable: B-cell cloning, hybridoma generation, FACS, automation, Octet (or other biochemical methods of affinity measurement), and developability assays.
  • Familiarity with murine immunizations and high-throughput screening is a plus.
  • Fluency in spoken and written English is mandatory. Fluency in Italian is a plus.